血浆置换治疗药物性肝衰竭56例疗效分析

Efficacy analysis of plasma exchange therapy in 56 patients with drug-induced liver failure

目的分析血浆置换治疗药物性肝衰竭的效果。方法回顾性分析56例药物性肝衰竭患者的临床资料。结果抗结核药物联合应用易出现药物性肝衰竭。血浆置换治疗能提高药物性肝衰竭的治愈率,缩短治愈患者的住院时间,且不良反应率低。结论血浆置换能提高药物性肝衰竭患者的治愈率,是治疗药物性肝衰竭的有效方法之一。

Objective To analyze the therapeutic effect of plasma exchange in the treatment of the patients with drug-in- duced liver failure. Methods The clinical data in 56 cases of drug-induced liver failure were retrospectively analyzed. Results The anti-TB drugs combination use was prone to induce liver failure. The plasma exchange therapy could increase the cure rate of drug-induced liver failure and shorten the patient＇s hospital stay with the low incidence of adverse reactions. Conclusion Plasma exchange can improve the cure rate of the patients with drug-induced liver failure and is one of effective methods for treatment of drug-induced liver failure.