穴位埋线加孟鲁司特治疗小儿支气管哮喘慢性持续期临床观察

Observation on the Clinical Efficacy of Acupoint Thread-embedding Combined with Montelukast Therapy for Pediatric Bronchial Asthma in the Chronic Persistent Phase

目的:观察穴位埋线加孟鲁司特治疗小儿支气管哮喘慢性持续期的临床疗效。方法:将60例小儿支气管哮喘慢性持续期患儿随机分为治疗组(穴位埋线﹢孟鲁司特口服)和对照组(孟鲁司特口服)。对照组单用孟鲁司特治疗,6～14岁,5 mg;2～5岁,4 mg,均每日1次。治疗组在对照组的基础上取大椎、定喘、肺俞、肾俞、足三里、丰隆为主穴予穴位埋线。治疗3个月后对比观察疗效及血清IgE、IL-4水平。结果:治疗组有效率为86.67%,对照组有效率为73.33%,两组疗效比较,差异有统计学意义(P<0.05)。治疗后血清IgE、IL-4水平均降低。结论:穴位埋线加孟鲁司特治疗小儿支气管哮喘慢性持续期疗效确切,能改善患者临床症状,且能降低血清IgE、IL-4水平。

Objective：To observe the clinical efficacy of acupoint thread-embedding for pediatric bronchial asthma in the chronic persistent phase.Methods：Sixty patients suffering bronchial asthma in the chronic persistent phase were randomly divided into treatment group and control group.The treatment group were given acupoint thread-embedding on mainly acupoints including Da zhui,Ding chuan,Fei shu,Shen shu,Zu sanli and Feng long,together with oral montelukast therapy with daily dose of 5mg in patients between 6 and 14 years old,for patients between 2 and 5 years old,the oral dose was 4mg daily.While patients in the control group were given oral montelukast only.Then observe the clinical efficacy and levels of sero IgE and IL-4 after three months therapy.Results：The total effective rate was 86.67%,which was higher than that in the control group（73.33%）.The difference between the two groups was significant（P0.05）.The levels of serum IgE and IL-4 was decreased significantly in the therapy group.Conclusions：The clinical efficacy of acupoint thread-embedding for pediatric bronchial asthma in the chronic persistent phase is definite,which can improve clinical symptoms and decrease levels of serum IgE and IL-4.