摘要
用Northern印迹分析艾灸结合免疫调节剂抑制肿瘤细胞增殖的机制。结果显示 ,艾灸及其结合免疫调节剂可明显降低c erbB 2mRNA的表达水平。表明艾灸及其结合免疫调节剂抑制肿瘤细胞增殖 ,可能与下调c erbB 2基因转录水平 。
Molecular biological mechanism of the action of moxibustion combined with immunomodulator was investigated, using the mice which were subcutaneously transplanted with H 22 (Haptoma) cell line as a solid carcinoma model. The result showed that c erbB 2 mRNA expression level was obviously reduced in tumor tissue in moxibustion group and group moxibustion and immunomodulator combination(group M+IM),as compared with tumor control group. The result implied that inhibition of tumor cell proliferation by moxibustion and immunomodulator combination was related to the reduction of c erbB 2 mRNA through decreasing rates of c erbB 2 gene transcription.
出处
《针刺研究》
CAS
CSCD
2000年第1期43-45,共3页
Acupuncture Research
基金
国家自然科学基金!(No .395 70 882 )
上海市卫生局科研课题资助
