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伏康树中生物碱化学成分研究 被引量：5

Study on the Alkaloids Constituents from Voacanga africana
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摘要 目的:研究伏康树中生物碱部分的化学成分。方法:采用正相硅胶、Sephadex LH-20等色谱方法进行分离纯化,并运用波谱分析的方法鉴定化合物结构。结果:分离并鉴定了8个生物碱类化合物,分别为:voacangine(1)、voacangine hydroxyindolenine(2)、19R-epi-voacristine(3)、epi-ibogaine(4)、vobasine(5)、19-epi-heyneanine(6)、vobtusine(7)和voacamine(8)。结论:其中,化合物2～4、6均为首次从该植物中分离得到。 Objective：To study the alkaloids of Voacanga africana.Methods：The alkaloids were isolated by normal phase silica gel and Sephadex LH-20 column chromatography.Their structures were elucidated by analysis of spectroscopic data.Results：Eight alkaloids were isolated and their structures were elucidated as voacangine（1）,voacangine hydroxyindolenine（2）,19R-epi-voacristine（3）,epi-ibogaine（4）,vobasine（5）,19-epi-heyneanine（6）,vobtusine（7） and voacamine（8）.Conclusion：Compounds 2~4 and 6 are isolated from this plant for the first time.
作者 梅玲 邓赟 李甫 郭大乐 陆崇玉
机构地区 成都中医药大学药学院中药材标准化教育部重点实验室/中药资源系统研究与开发利用省部共建国家重点实验室培育基地 中国科学院成都生物研究所
出处 《中药材》 CAS CSCD 北大核心 2012年第2期226-229,共4页 Journal of Chinese Medicinal Materials
基金 四川省杰出青年学术技术带头人资助计划(2010JQ0036)
关键词 伏康树 生物碱 化学成分 Voacanga africana Staph. Alkaloids Chemical constituents
分类号 R284.1 [医药卫生—中药学] R284.2 [医药卫生—中药学]
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参考文献9

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共引文献19

同被引文献54

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引证文献5

二级引证文献12

中药材
2012年 第2期

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