生力胶囊质量标准的研究

Study on Quality Standards of Shengli Capsules

目的:提高生力胶囊的质量标准。方法:采用薄层色谱法鉴别生力胶囊中的丁香、枸杞子;采用高效液相色谱法测定生力胶囊中人参皂苷Rg1、Re的含量。结果:丁香、枸杞子的薄层色谱法鉴别专属性强,分离效果好;人参皂苷Rg1在0.0526～0.5260 mg·mL-1的浓度范围内,浓度与峰面积呈良好线性关系,平均回收率为93.1%(RSD=0.9%);人参皂苷Re在0.05208～0.5208 mg·mL-1的浓度范围内,浓度与峰面积呈良好线性关系,平均回收率为93.7%(RSD=1.3%)。结论:本方法准确,重现性好,可用于控制生力胶囊的质量。

Objective： To improve the quality standards of Shengli Capsules. Methods： An TLC method was used to identify cloves, and wolfberry fruit in Shengli Capsules, and determination of content of ginsenoside Rg1 , ginsenoside Re with HPLC method. Results： Cloves and wolfberry fruit in Shengli Capsules were excellent identified by TLC, a strong specificity, a better effect on separation. The linear range of Ginsenosides Rgl and Ginsenosides Re were 0. 0526 -0. 5260mg · mL-land 0. 05208 -0. 5208 mg· mL- 1;The average recoveries were 93. 1% （RSD =0. 9% ） and 93.7% （RSD = 1.3% ）. Conclusion： The method is accurate, reliable and can be used to the quality control of Shengli Capsules.