11种蒙成药微生物限度检查方法的探讨

Study on the Microbial Limit Test of 11 Kinds of Traditional Mongolian Medicine

目的:建立11种蒙成药的微生物限度检查方法。方法:采用6种阳性对照菌回收率试验测定其是否含抑菌成分。结果:根据回收率试验结果,胡日查六味丸、寒水石二十一味散、利胆八味散、哈日十二味散和清热八味散5种药品试验菌的回收率试验均高于70%,证明无抑菌现象;吉祥安坤丸、羚牛角二十五味丸、阿拉担五味散、石膏二十五味散、清肾热十味散、清咽六味散6种药品有一定程度的抑菌作用,但可通过稀释法消除抑菌作用。结论:确立了11种蒙成药微生物限度检查方法。

Objective： To establish an method for microbial limit test of 11 kinds of traditional Mongolian medicine. Method ：The recovery test with 6 position control bacterial strains for the determination of whether these 11 kinds of traditional Mongolian medicine containing inhibiting bacterial components. Results： Huricha Liuwei Pills, Hanshuishi Ershiyiwei Powder, Lidan Bawei Powder, Haft Shibawei Powder and Qinger Bawei Powders. The bacterial recovery were higher than 70% in both of them, it shows that they do not contain inhibiting bacterial components. Jixiang Ankun Pills, Lingniujiao Eeshiwuwei Pills, Aladan Wuwei Powder, Shigao Ershiwuwei Powder, Qingshenre Shiwei Powder, Qingyan Liuwei Powder, they contain inhibiting bacterial components, but they may be diluted to eliminate the inhibiting beaterial effect. Conclusion： We establish a method for microbial limit test of 11 kinds of traditional Mongolian medicine.