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毛母质瘤临床与病理回顾性分析 被引量:8

A RETROSPECTIVE STUDY OF CLINIAL AND PATHOLOGICAL FEATURES IN PILOMATRICOMA
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摘要 目的:研究毛母质瘤临床、病理特征。方法:回顾分析43例毛母质瘤临床资料和组织病理检查结果。结果:多数病人为单发皮损(占95.35%);发病年龄30岁以下占86.05%,男女比例1∶1.39;好发于面颈部、上肢,肿瘤直径0.3~2.5cm。临床与病理诊断的符合率为11.63%。毛母质瘤4种特征性病理改变(影细胞、嗜碱细胞、过渡细胞和钙化)的发生率分别为100%、68.89%、48.89%和24.44%。结论:毛母质瘤是一种缓慢生长的良性皮肤肿瘤,临床表现多样化,易误诊,临床上需要与皮脂腺囊肿、皮肤纤维瘤、表皮囊肿、血管瘤等疾病相鉴别。因此发生于面颈部、上肢的硬性结节应当完整手术切除后行组织病理检查以明确诊断。 Objective:To investigate the clinical and pathological features of pilomatricoma. Meth- od:Clinical manifestations and pathological findings of 43 patients with pilomatrieoma were retrospectively investigated. Result:Single lesion occurred in most patients (95.35 % )and 86.05 % of them were younger than 30 years. The male - female ratio was 1 : 1.39. The lesions which sizes ranged from 0. 3 to 2.5cm were commonly emerged in the cheeks, neck, and upper extremity. The correct diagnosis was made preoperatively in 5 patients ( 11.63 % ). The presence of ghost cells, basaloid cells, transition cells and calcification in slide was 100% , 68. 89% , 48.89% and 24.44% , respectively. Conclusion: Pi- lomatricoma is a slowly growing benign cutaneous tumour. The manifestation is diversed and easily mis- diagnosed. The differential diagnoses including atheromatous cyst, dermatofibroma, epidermal cyst and angioma are needed in clinic. Biopsy after complete surgical excision is recommended for nodules on head, neck and upper extremity.
出处 《内蒙古医学院学报》 2012年第2期108-112,共5页 Acta Academiae Medicinae Neimongol
基金 国家自然科学基金<银屑病与系统性红斑狼疮共同易感基因TNIP1和TNFAIP3基因精细定位研究>(编号31160192)资助
关键词 毛母质瘤 临床表现 组织病理 Pilomatricoma clinical manifestations histopathology
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参考文献19

  • 1石国光.毛母质瘤26例临床分析[J].中国皮肤性病学杂志,2004,18(8):477-478. 被引量:11
  • 2何弘,高天文,李青,马福成,黄慧,黄高升.146例毛母质瘤临床回顾[J].临床皮肤科杂志,2002,31(2):79-80. 被引量:36
  • 3Wang J,Cobb CJ,Martin SE,et al.Pilomatrixoma:clinico-pathologic study of 51 cases with emphasis on cytologicfeatures[J].Diagn Cytopathol,2002;27(3):167-172.
  • 4Van der Horn G,Rutten MJ.Pilomatrixoma[J].JBR-BTR,2011;94(3):142-143.
  • 5Guinot-Moya R,Valmaseda-Castellon E,Berini-AytesL,et al.Pilomatrixoma.Review of 205 cases[J].Med OralPatol Oral Cir Bucal,2011;16(4):e552-555.
  • 6O'Connor N,Patel M,Umar T,et al.Head and neck piloma-tricoma:an analysis of 201 cases[J].Br J Oral MaxillofacSurg,2011;49(5):354-358.
  • 7彭军,邢卫斌.毛母质瘤14例临床与病理分析[J].临床皮肤科杂志,2008,37(1):27-27. 被引量:13
  • 8Kakarala K,Brigger MT,Faquin WC,et al.Cystic piloma-trixoma:a diagnostic challenge[J].Arch Otolaryngol HeadNeck Surg,2010;136(8):830-833.
  • 9Roche NA,Monstrey SJ,Matton GE.Pilomatricoma in chil-dren:common but often misdiagnosed[J].Acta Chir Belg,2010;110(2):250-254.
  • 10Bansal C,Handa U,Mohan H.Fine needle aspiration cy-tology of pilomatrixoma[J].J Cytol,2011;28(1):1-6.

二级参考文献34

  • 1吕宏升,朱庆生,王军,朱锦宇,赵广跃,张大伟.全自动显微镜及图像分析系统处理免疫组化图像[J].中国体视学与图像分析,2004,9(1):37-40. 被引量:63
  • 2刘勤,张健.毛母质瘤82例临床与病理分析[J].中国麻风皮肤病杂志,2007,23(7):589-590. 被引量:9
  • 3Demirkan NC,Bir F,Erdem O,et al.Immunohistochemical expression of beta-catenin,e-cadherin,cyclin D1 and c-myc in benign trichogenic tumors.J Cutan Pathol 2007;34(6):467-473.
  • 4Xia J,Urabe K,Moroi Y,et al.Beta-catenin mutation and its nuclear localization are confirmed to be frequent causes of Wnt signaling pathway activation in pilomatricomas.J Dermatol Sci 2006;41(1):67-75.
  • 5Huelsken J,Vogel R,Erdmann B,et al.Beta-catenin controls hair follicle morphogenesis and stem cell differentiation in the skin.Cell 2001;105(4):533-545.
  • 6Del Sordo R,Cavaliere A,Sidoni A.Basal cell carcinoma with matrical differentiation:expression of beta-catenin[corrected] and osteopontin.Am J Dermatopathol 2007;29(5):470-474.
  • 7Maruyama K,Ochiai A,Akimoto S,et al.Cytoplasmic beta-catenin accumulation as a predictor of hematogenous metastasis in human colorectal cancer.Oncology 2000;59(4):302-309.
  • 8Hassanein AM,Glanz SM.Beta-catenin expression in benign and malignant pilomatrix neoplasms.Br J Dermatol 2004;150(3):511-516.
  • 9Kajino Y,Yamaguchi A,Hashimoto N,et al.Beta-Catenin gene mutation in human hair follicle-related tumors.Pathol Int 2001;51(7):543-548.
  • 10Lazar AJ,Calonje E,Grayson W,et al.Pilomatrix carcinomas contain mutations in CTNNB1,the gene encoding beta-catenin.J Cutan Pathol 2005;32(2):148-157.

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