急性阑尾炎术后预防感染的两种方案成本-效果比较

Cost-effectiveness comparison of two drug treatment programs for the prevention of infection after appendectomy

目的评价两种急性阑尾炎术后预防感染方案的成本与效果,促进临床治疗方案的合理选择。方法选择118例急性阑尾炎术后患者,按照不同的给药方案分为A、B两组,A组(n=58)给予别注射头孢哌酮钠舒巴坦钠+甲硝唑氯化钠注射液,B组(n=60)给与盐酸左氧氟沙星注射液+甲硝唑氯化钠注射液,用药物经济学方法进行分析。结果 A、B两组的有效率分别为:94.8%、83.3%;平均总医疗成本分别为:299.93元、285.35元;成本-效果比分别为:3.16、3.43。结论从药物经济学的角度,A方案为两种方案中用于急性阑尾炎术后预防感染的较优方案。

Objective To evaluate the cost and effectiveness of two drug treatment programs for the prevention of infection after appendectomy,and promote the rational choice of clinical treatment.Methods 118 patients undergoing appendectomy and received two drug treatment programs（A and B）,group A（n=58） were treated with Cefoperazone/Sulbactam Sodium＋Metronidazole and Sodium Chloride injection,and group B（n=60） with Levofloxacin Hydrochloride injection＋Metronidazole and Sodium Chloride injection,2 drug treatment programs were analyzed and evaluated with pharmacoeconomics.Results The effective rates of group A and group B were 94.8% and 83.3%,the costs were 299.93 yuan and 285.35 yuan,the cost-effectiveness ratios were 3.16 and 3.43,respectively.Conclusion From the perspective of pharmacoeconomics,treatment program A is optimal in the treatment of the prevention of infection after appendectomy among the two treatment programs.