老年腹膜透析患者微炎症与营养状况及透析充分性间关系的探讨

Analysis on relationship between micro-inflammatory state,nutritional status and dialysis adequacy in senile peritoneum dialysis patients

目的探讨老年腹膜透析(peritoneal dialysis,PD)患者微炎症状态、营养状况与透析充分性的关系。方法按照超敏C-反应蛋白(hs-CRP)≤5 mg/L和hs-CRP>5 mg/L,将腹膜透析患者分为两组,比较两组间营养状况指标及透析充分指标与炎症指标的关系。结果两组患者血清白蛋白(ALB)、转铁蛋白(TF)、前白蛋白(PA)、血红蛋白(HGB)、hs-CRP、尿素清除率(Kt/V)、标准化蛋白分解率(nPCR)、改良定量主观整体评估(MQSGA)间差异有统计学意义(P<0.05)。结论老年腹膜透析患者存在微炎症状态。微炎症状态与营养不良及透析充分性密切相关。

Objective To analyze the relationship between micro-inflammatory state,nutritional status and dialysis adequacy in senile peritoneum dialysis（PD） patients.Methods The senile peritoneal dialysis patients were divided into high-sensitive C-reactive protein（hs-CRP）≤5mg/L and hs-CRP〉5mg/L group.The level of micro-inflammatory state,nutritional status and dialysis adequacy were compared between these two groups.Results There was statistical significance in difference of ALB,TF,PA,HGB,hs-CRP,Kt/V,Npcr and MQSGA between two groups（P〈0.05）.Conclusion There was micro-inflammatory state,with senile peritoneum dialysis patients and a close relationship between micro-inflammatory state,nutritional status and dialysis adequacy.