肺部炎性肌纤维母细胞瘤的CT诊断

CT Diagnosis of pulmonary inflammatory myofibroblastic tumor

目的探讨肺部炎性肌纤维母细胞瘤(IMT)的CT表现及其临床诊断价值。方法回顾性分析经手术病理证实的8例肺部IMT患者的CT表现,其中5例行CT平扫检查,3例行平扫+增强扫描检查。结果 8例患者3例为中央型,CT表现为边界不清的实变灶;5例为周围型,表现为边界清楚的软组织密度肿块或结节;增强后肿块实性部分呈均匀或不均匀中度或明显强化,坏死、囊变区无明显强化。病理示肿瘤由梭形细胞及炎症细胞组成,免疫组织化学染色肌源性蛋白阳性表达。结论 IMT是一种少见的肿瘤,CT检查能为其提供准确的解剖部位等信息,在定性诊断方面有一定价值,但最后确诊还有赖于组织病理学及免疫组织化学检查。

Objective To investigate the CT features of pulmonary inflammatory myofibroblastic tumor（IMT） and their value in the clinical diagnosis.Methods The CT findings of 8 cases with pathology proven IMT were retrospectively analyzed.Of which,5 cases had plain CT and 3 cases had plain and enhancement scanned.Results In these 8 patients there were 3 central lesions presented as solid masses with obscure boundary margin;5 peripheral lesions as solid masses or nodules with well-defined margin.Moderate or marked homogeneous or heterogeneous enhancement was shown in the solid part of tumor,cystic and necrotic without marked enhancement.Tumors were mainly composed of spindle shaped fibrous cells and inflammatory cells on pathology.On immunohistochemistry staining,positive expression of muscle deriving proteins was observed.Conclusion IMT is a kind of rare tumor,the final diagnosis of IMT relies on pathology and immunohistochemistry study;CT examination provides information of accurate anatomic location and are helpful for the clinical diagnosis.