Synthesis and Biological Evaluation of Andrographolide C-Glycoside Derivatives as a-Glycosidase Inhibitors

Synthesis and Biological Evaluation of Andrographolide C-Glycoside Derivatives as a-Glycosidase Inhibitors

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摘要 A series of new andrographolide C-glycoside derivatives were synthesized by a facile route. The new com- pounds showed higher potency than the parent andrographolide evaluated as a-glycosidase inhibitors in the pre- liminary study. A series of new andrographolide C-glycoside derivatives were synthesized by a facile route. The new com- pounds showed higher potency than the parent andrographolide evaluated as a-glycosidase inhibitors in the pre- liminary study.

作者严琳徐海伟刘丰五赵瑾刘宏民

机构地区 Institute of Chemistry&Biology New Drug Research&Development Center

出处《Chinese Journal of Chemistry》 SCIE CAS CSCD 2012年第4期914-918,共5页 中国化学（英文版）

关键词 ANDROGRAPHOLIDE β-C-glycosidic ketone a-glycosidase inhibitor andrographolide, β-C-glycosidic ketone, a-glycosidase inhibitor

分类号 O629.13 [理学—有机化学] TQ461 [化学工程—制药化工]

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Chinese Journal of Chemistry

2012年第4期

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Synthesis and Biological Evaluation of Andrographolide C-Glycoside Derivatives as a-Glycosidase Inhibitors

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