米非司酮联合中药保守治疗异位妊娠的临床疗效观察

Clinical Analysis of Mifepristone Combined with Traditional Chinese Medicine in Treatment of Ectopic Pregnancy

目的:探讨米非司酮结合中药治疗异位妊娠的临床效果。方法:将临床确诊为未破裂异位妊娠患者,按入院日期的单双日随机分为两组,米非司酮结合中药治疗异位妊娠为观察组(50例),单纯用甲氨蝶呤治疗异位妊娠为对照组(50例)。比较两组治疗成功率、血β-HCG降至正常天数及其影响因素。结果:观察组治疗成功率84%,高于对照组治疗成功率70%,差异具有统计学意义(P<0.05);治疗组与对照组比较,血β-HCG降至正常所需的时间明显缩短、包块缩小快,两组间差异有统计学意义(P<0.05)。结论:米非司酮结合中药治疗异位妊娠疗效高、疗程短、不良反应少,具有推广价值。

Objective：To investigate effects of medical treatment on ectopic pregnancy by mifepristone combined with traditional Chinese medicine.Methods： Patients with ectopic pregnancy were divided randomly into observation group（50 cases）and control group（50 cases） by admission date.Patients in observation group were treated by mifepristone combined with traditional Chinese medicine and patients in control group were treated by amethopterin.Compare the treatment success rate,time for serum β-HCG reduced to normal and its influencing factors between the two groups.Results： The treatment success rate in observation group（84%） was higher than that in control group（70%）,with statistical significance（P〈0.05）;The time time for serum β-HCG dropped to the normal value was obviously shorter in observation group than in control group and the reduction of block was more quickly;differences were statistically significant between the two groups（P〈0.05）.Conclusions： Combination of mifepristone with traditional Chinese medicine is effective and safe in the conservative therapy of ectopic pregnancy,and deserves popularization.