摘要
以藤黄酸和N-苄基苦参醇为原料,在1-(3-二甲胺丙基)-3-乙基碳二亚胺盐酸盐(EDCI)和4-二甲氨基吡啶(DMAP)的作用下合成了目标产物N-苄基苦参醇藤黄酸酯,并研究了其合成的优化工艺。结果表明:设计合成方法收率达到61.8%。产物的化学结构经IR、MS、1H NMR等得到确证。
N- Benzyl kurarinol gambogate was synthesized and the technical process was optimized, through Gam- bogie acid conjugated with N - Benzyl kurarinol. The target compound was obtained. Its chemical structure was confirmed by MS, IR, and 1H- NMR spectra. The yield of N-Benzyl kurarinol gambogate was 61.8%.
出处
《广州化工》
CAS
2012年第8期85-86,共2页
GuangZhou Chemical Industry
基金
安徽省高校优秀青年教师基金项目(2009SQRZ113)
关键词
N-苄基苦参醇
藤黄酸
合成
N - Benzyl kurarinol
Gambogic acid
synthesis
