成本-效果分析在消化性溃疡治疗方案中的应用

Application of Cost-effectiveness Analysis of Therapeutic Scheme of Peptic Ulcer

目的 :为了探讨不同药物治疗方案对同一疾病所产生的经济效果。方法 :根据文献选择了 13 5例胃溃疡病患者 ,随机分为 4组 ,给予不同治疗方案 (A :十六角蒙脱石 +雷尼替丁 ;B :雷尼替丁 ;C :奥美拉唑 ;D :胶体次枸橼酸铋 ) ,运用药物经济学的成本 效果分析方法进行评价。结果 :A方案为最佳治疗方案。结论 :药物经济学在优化治疗方案 ,指导合理用药 。

Objective:In order to evaluate the economic effectiveness in different pharmacotherapeutic schemes for the same disease. Methods:135 patients with peptic ulcer were selected from literature reports. These patients were radomly divided into four groups which received different therapeutic schemes (A:dioctahedral smectite+ranitidine; B:ranitidine; C:omprazole; D:colloidal bismuth subcitrate). Their economic effectiveness were evaluated by pharmacoeconomic cost effectiveness analysis. Results:A was the best scheme. Conclusion:Pharmaconomics is very important in selecting optimizing therapeutic scheme, guiding rational use of drug and increasing economic effectiveness.