缩泉胶囊配合酒石酸托特罗定治疗膀胱过度活动症肾虚型36例疗效观察

Observation of Suoquan capsule combined with Tolterodine tartrate on overactive bladder

目的观察缩泉胶囊配合酒石酸托特罗定治疗膀胱过度活动症肾虚型临床疗效。方法将68例膀胱过度活动症肾虚型患者随机分为2组,对照组32例予酒石酸托特罗定治疗,治疗组36例在对照组治疗基础上加用缩泉胶囊治疗。2组均6周为1个疗程,1个疗程后观察治疗前后24 h平均排尿次数、平均24 h尿失禁次数、每次排尿量和不良反应例数。结果治疗组治疗后24 h平均排尿次数少于对照组(P<0.05),每次排尿量多于对照组(P<0.05)。2组治疗后平均24 h尿失禁次数比较差异无统计学意义(P>0.05)。治疗组不良反应率低于对照组(P<0.05)。结论缩泉胶囊配合酒石酸托特罗定治疗膀胱过度活动症肾虚型疗效确切。

Objective To observe the therapeutic effect of Suoquan capsule combined with Tolterodine tartrate on overactive bladder.Methods 68 cases of overactive bladder were randomly divided into treatment group（n=36）,which were treated by Suoquan capsule combined with Tolterodine tartrate and control group（n=32）,which were given Tolterodine tartrate.The course was six weeks in two groups.The average frequency of urination before and after treatment for 24 h,the average 24-h urinary incontinence,each voided volume and adverse reaction cases were recorded after a course.Results The average frequency of urination after treatment for 24 h was decreased as compared with that before treatment in treatment group,and each voided volume was increased（P0.05）.There was no significant difference between two groups on the average 24-h urinary incontinence after treatment.Adverse reaction cases in treatment group was lower than that in control group（P0.05）.Conclusion Suoquan capsule combined with Tolterodine tartrate has positive effect on overactive bladder.