普萘洛尔治疗婴幼儿血管瘤并发溃疡形成的效果与护理

Nursing and effect of propranolol combined with local therapy on hemangioma infancy with ulceration

目的探讨普萘洛尔联合局部治疗婴幼儿血管瘤并发溃疡形成的效果，分析其有效的护理方法。方法将64例婴幼儿血管瘤并溃疡形成患儿按照住院时间分为两组，传统治疗组43例，采用局部治疗为主的方法；普萘洛尔治疗组21例，采用在传统治疗方法的基础上给予口服普萘洛尔治疗，针对治疗过程中出现的局部出血、局部疼痛、腹泻及心率过低实施有效的护理措施，比较两组之间治疗效果。结果两组患儿均治愈；普萘洛尔治疗组治疗的时间（21±7．3）d，短于传统治疗组（56±18．9）d；局部瘢痕发生率14．3％，低于传统治疗组60．5％，差异均有统计学意义（t=19．356，x2=12．14；P〈0．05）。结论婴幼儿血管瘤并溃疡形成在传统局部创面治疗的基础上给予口服普萘洛尔治疗，同时给予有效的护理能够加速创面的愈合，减少并发症的发生。

Objective To explore the effect of propranolol combined with part therapy on hemangioma infancy with ulceration and analyse the effective nursing care methods. Methods A total of 64 hemangioma infancy with ulceration were divided into two group by the time of hospitalized, and 43 cases in traditional therapy group received the traditional therapeutic method that focus on local therapeutics from January 2005 to April 2009, and 21 cases in propranolol therapy group received oral propranolol therapy with a dose of 1.5 - 2.0 mg per kilogram of body weight per day on the basis of traditional therapeutic method from May 2009 to June 2011. Health education, closely vital sign monitored and effectively nursing intervention for local bleeding, local pain, diarrhea and less heart rate were implemented during the therapeutic process, and then the therapeutic effects of two groups were compared. Results All cases were cured, but the therapeutic time of the propranolol group was significantly less than that of the traditional group [ （21 ± 7.3 ） d vs （ 56 ± 18.9 ） d; t = 19. 356, P 〈 0.01 ） ] , and the incidence rate of local scar in the propranolol group was also significantly less than that in the traditional group （ 14% vs 60% ; X2 = 12. 14, P 〈 0. 05 ）. Conclusions Oral propranolol combined with effective nursing care on the basis of traditional therapeutic method which focus on local therapeutics can accelerate the ulceration heal and decrease the incidence of complications.