颞骨孤立性骨浆细胞瘤的临床特征

Clinical characteristics of solitary plasmacytoma of temporal bone

目的总结以往文献报道的颞骨孤立性骨浆细胞瘤的临床特征、诊断和治疗,为其临床诊治提供依据。方法通过本文报道的1例颞骨孤立性骨浆细胞瘤及复习往文献报道的病例,对11例颞骨孤立性骨浆细胞瘤的症状体征、实验室检查、影像学、病理、诊断、治疗和预后进行比较分析。结果 11例颞骨孤立性骨浆细胞瘤病例中所有病例均有不同程度的听力下降,耳局部症状明显,其中9例有颅神经损害症状,骨质破坏明显。结论浆细胞瘤是源于B淋巴细胞的恶性肿瘤,原发于颞骨的孤立性浆细胞瘤极为罕见,诊断主要依靠临床表现、影像学和病理,治疗方法为手术和放疗。

Objective To summarize the clinical characteristics,diagnosis and treatment of solitary plasmacytoma of temporal bone from literature report to provide the clinical evidence.Methods 11 lasmacytoma of temporal bone were reported in the available literature,we analyzed the clinical characteristics,Laboratory studies,imaging examination,histopathology,diagnosis and therapeutic approaches of these cases.Results There were different degrees for hearing loss in all of the cases with evident symptom in unilateral ear;while 9 of them suffered from obvious damage of cranial nerve and bone.Conclusions Plasmacytoma is a malignancy which derived from B lymphocytes,it＇s really rare in temporal bone when they are solitary.Clinical characteristics,imaging examination and histopathology can establish an accurate diagnose.The therapy will be surgery and followed radiotherapy.