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微波消融联合肝动脉栓塞化疗术治疗中晚期肝癌的临床研究 被引量:4

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摘要 目的观察微波消融治疗术(Microwave Coagulation Therapy,MCT)联合肝动脉栓塞化疗术(Transcatheter Arterial Chemoemoembolization,TACE)治疗中晚期肝癌的临床效果。方法 106例中晚期肝癌患者中,78例采用MCT联合TACE治疗为观察组,其中的42例TACE术后1周联合MCT治疗为观察A组,36例术后2周联合MCT治疗为B组;28例单纯采用TACE治疗为对照组。用SPSS13.0软件分析观察组和对照组、观察A组和B组间术后1个月肝癌病灶碘油沉积率和AFP下降率,以及一年生存率的差异。结果①术后1个月AFP降幅良好率观察组为71.8%,对照组为42.9%;碘油沉积良好率观察组为75.6%,对照组为46.4%;1年生存率观察组为52.6%,对照组为25.9%,两组相比观察组优于对照组,P<0.01,均具有统计学意义。②观察组中术后1个月观察:AFP降幅良好率A组为83.3%,B组为58.3%;碘油沉积良好率A组为85.7%,B组为63.9%;1年生存率A组为64.3%,B组为38.9%,A组优于B组,P<0.05,均有统计学意义。结论 MCT联合TACE治疗中晚期肝癌,疗效优于单独TACE治疗;TACE术后1周内行MCT治疗,能更有效地形成碘油沉积和降低AFP、提高生存率。TACE术后尽早联合MCT对控制肿瘤、提高生存率有较好的效果。
出处 《微创医学》 2012年第2期131-132,共2页 Journal of Minimally Invasive Medicine
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