六黄合剂对胰岛素抵抗大鼠糖耐量和血清胰岛素的影响

Effects of Liuhuang on the glucose tolerance and serum insulin in animal models of insulin resistance

目的探讨六黄合剂对胰岛素抵抗大鼠糖耐量和血清胰岛素的影响。方法应用地塞米松致大鼠胰岛素抵抗(IR)模型,观察六黄合剂对大鼠血糖、血清胰岛素的变化。结果六黄合剂能够降低胰岛素抵抗大鼠口服葡萄糖耐量试验后2h血糖浓度(2hBG)和空腹血清胰岛素水平(FINS)(P<0.01)。结论六黄合剂可以改善葡萄糖耐量减退(IGT)和IR。

Objective To investigate the effects of Liuhuang on the animal models of insulin resistance（IR）.Methods IR rat model with dexamethasone was used,give intervention of Liuhuang.Results Liuhuang lowered 2-hour blood glucose（2 hBG）after oral glucose tolerance test and fast insulin（FINS）（P〈0.01）.Conclusion Liuhuang can enhance impaired glucose tolerance（IGT）and IR.