期刊文献+

电子自旋共振-自由基捕获技术在生物学中的应用 被引量:1

Applications of Electron Spin Resonance in Biology
原文传递
导出
摘要 本文结合作者实验室的工作,简要回顾了电子自旋共振-自由基捕获技术在生物领域的应用,包括新型自由基捕获探针的分子设计与合成,以及该技术在细胞、植物体系中的应用实例,并结合该技术的研究现状初步讨论了它的未来发展前景。 In this review, we briefly summarized the application of electron spin resonance in biology, including the molecular design and synthesis of new spin traps and the applications of spin-trapping in plants and cells. Based on the present status of spin trapping research, finally, we discussed the prospects for the future development of the spin trapping.
作者 杜立波 刘扬
出处 《生物物理学报》 CAS CSCD 北大核心 2012年第4期259-267,共9页 Acta Biophysica Sinica
基金 中国科学院知识创新工程项目(KJCX2-EW-H01)~~
关键词 自由基 自由基捕获技术 电子自旋共振 Free radicals Spin trapping Electron spin resonance
  • 相关文献

参考文献27

  • 1Roubaud V, Mercier A, Olive G, Le MF, Tordo P. 5.(iethoxyphosphorylmethyl)-5-methyl-4,5-dihydro-3H-pyrrole N-oxide: Synthesis and evaluation of spin trapping properties. J Chem Soc Perkin Trans, 1997, 2: 1827-1830Jiethoxyphosphorylmethyl)~.
  • 2Robinson EA, Johnson JD. Methods for analysis of free radicals in cigarette smoke. Mini-Rev Org Chem, 2011, 8: 401 -411.
  • 3Rhodes CJ. Electron spin resonance. Part one: A diagnostic method in the biomedical sciences. Sci Prog, 2011, 94: 16-96.
  • 4Freinbichler W, Colivicchi MA, Stefanini C, Bianchi L, Ballini C, Misini B, Weinberger P, Linert W, Vareslija D, Tipton KF, Della Corte L. Highly reactive oxygen species: Detection, formation, and possible functions. Cell Mol Life Sci. 2011. 68:2067-2079.
  • 5Afanasev L. Detection of superoxide in cells, tissues and whole organisms. Front Biosci, 2009, 1:153-160.
  • 6Ouari O, Chalier F, Bonaly R, Pucci B, Tordo P. Synthesis and spin-trapping behavior of glycosylated nitrones. J Chem Soc Perkin Trans, 1998, 2:2299-2307.
  • 7Ouari O, Polidori A, Pucci B, Tordo P, Chalier F. Synthesis of a glycolipidic amphiphilic nitrone as a new spin trap. J Org Chem, 1999, 64:3554-3556.
  • 8Durand G, Polidori A, Ouari O, Tordo P, Geromel V, Rustin P, Pucci B. Synthesis and preliminary biological evaluations of ionic and nonionic amphiphilic alphaphenyI-N-tert-butylnitrone derivatives. J Med Chem, 2003, 46:5230-5237.
  • 9Saito K, Takahashi M, Kamibayashi M, Ozawa T, Kohno M. Comparison of superoxide detection abilities of newly developed spin traps in the living ceils. Free Radic Res, 2009, 43:668-676.
  • 10Hay A, Burkitt M J, Jones CM, Hartley RC. Development of a new ESR spin trap, DOD-8C (N-[4-dodecyloxy-2-(7'carboxyhept-l'-yloxy)benzylidene]-N-tert-butylamine N-oxide), for the trapping of lipid radicals at a predetermined depth within biological membranes. Arch Biochem Biophys, 2005, 435:336-346.

二级参考文献4

  • 1赵保路,Acta Biophys Sin,1994年,10卷,174页
  • 2赵保路,Chin Sci Bull,1990年,35卷,56页
  • 3赵保路,氧自由基和天然抗氧化剂,1999年,7页
  • 4Chen G X,Biochemistry,1992年,31卷,11072页

共引文献15

同被引文献26

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部