抗肝纤维化的中药有效成分及其作用机制研究进展

Advances in active ingredients and action mechanism of TCM in treatment of hepatic fibrosis

肝纤维化是多数慢性肝病所共有的病理特征,肝纤维化逐步发展形成肝硬化,最终导致肝癌。本文将近年报道的具有抗HF作用的中药有效成分作简单综述,归纳为黄酮类、生物碱类、萜类、酚类化合物,并总结了各类有效成分抗HF的作用机制,为深入开展中药抗HF的研究提供一定的参考。

Hepatic fibrosis was the common feature of pathology in almost all patients with chronic liver injury,which led to cirrhosis gradually and liver cancer ultimately.The anti-hepatic fibrosis active ingredients from TCM,including flavones,alkaloids,terpenes and phenols compounds were reviewed with the action mechanism in this paper,which could provide some references for the further study about the anti-hepatic fibrosis of TCM.