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帕洛诺司琼预防妇科腹腔镜手术后恶心呕吐的临床研究 被引量:7

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摘要 目的观察帕洛诺司琼预防妇科腹腔镜手术后恶心呕吐的效果。方法择期全麻下行妇科腹腔镜手术的患者60例,随机分入帕洛诺司琼组(P组),昂丹司琼+地塞米松(D组),每组30例。麻醉诱导前各组分别静脉注射帕洛诺司琼0.25mg/10m(lP组),昂丹司琼4mg+地塞米松8m(gD组)。记录术后0~6h,6~12h,12~24h,24~48h四个时间段患者恶心呕吐的情况及完全缓解率(Complete Response Rate,CRR)。结果两组的术后6h、12h、24h和48h的CRR比较(P组vsD组):100%vs86.7%(P>0.05),100%vs66.7%(P<0.05),96.7%vs50%(P<0.05),83.3%vs50%(P<0.05)。各个观察时段内,P组恶心呕吐的发生率较D组少。结论与昂丹司琼复合地塞米松比较,帕洛诺司琼减少术后48小时的恶心呕吐发生率,是值得推荐的防治PONV药物。
出处 《当代医学》 2012年第14期16-17,共2页 Contemporary Medicine
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同被引文献56

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