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2-甲氧雌二醇对HL60白血病细胞凋亡的影响

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摘要 目的探讨2-甲氧雌二醇对HL60白血病细胞凋亡的影响。方法采用流式细胞计数检测2-甲氧雌二醇对HL60白血病细胞的增殖抑制作用。结果随着2-甲氧雌二醇的浓度增高,HL60白血病细胞的增殖受到抑制,对照组凋亡率为(1.2±0.3)%,实验组2-ME210μmol/L为(9.7±2.1)%,2-ME230μmol/L为(11.6±3.0)%,2-ME250μmol/L为(15.8±2.9)%。白血病细胞凋亡明显增加。结论 2-ME对IK60细胞增殖有抑制及促凋亡作用。
出处 《当代医学》 2012年第14期82-82,共1页 Contemporary Medicine
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