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乳头状甲状腺癌颈部淋巴结转移规律分析 被引量:4

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摘要 目的探讨乳头状甲状腺癌(PTC)颈部淋巴结转移规律,为合理选择清扫范围提供临床依据。方法回顾性分析2004年1月~2010年12月收治的236例PTC患者的临床病理资料。术后病理检查明确淋巴结转移的数目及范围。结果行双侧甲状腺全切除术42例,侧叶加峡部切除术194例。术后病理学诊断双侧甲状腺癌38例,单侧甲状腺癌198例。甲状腺肿瘤的直径0.3~6.0cm,平均3.5cm。肿瘤侵犯包膜的共54例,多灶性肿瘤共36例。术中冰冻结果确诊出现阳性淋巴结后行颈清扫淋巴结数目10~26枚,平均18.1枚。其中,中央组(VI区)淋巴结转移发生率为44.91%(106/236),颈深部组(II+III+IV区)淋巴结转移发生率为19.91%(47/236)。当肿瘤突破被膜、多灶性肿瘤、肿瘤直径>1.0cm、或年龄>45岁时VI区及II+III+IV区的同侧淋巴结转移发生率明显增加(P<0.05)。结论 PTC颈部淋巴结转移最常见的部位是中央组(VI区),其次为颈深部淋巴结(II+III+IV区)。初次手术应常规清扫VI区淋巴结。术前常规行细针细胞学诊断及影像学B型超声、CT检查怀疑颈部淋巴结转移时,须常规清扫II+III+IV区淋巴结。
出处 《当代医学》 2012年第14期103-104,共2页 Contemporary Medicine
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