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乳腺癌耐药蛋白的研究进展 被引量:4

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摘要 乳腺癌耐药蛋白 (BCRP)是新近发现的一种肿瘤耐药相关蛋白 ,与P gp和多药耐药相关蛋白 (MRP)同属ABC转运蛋白超家族。本文对BCRP的发现、基因转染、结构特点、组织表达和临床意义等方面研究进展进行综述。
机构地区 中国医学科学院
出处 《国外医学(肿瘤学分册)》 北大核心 2000年第2期71-72,共2页 Foreign Medical Sciences (Cancer Section)
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  • 1Ross DD,Yang WD,Abruzzo LV,et al.Atypical multidrug resistance:breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines.J Natl Cancer Inst,1999,91:429-433.
  • 2Chen YN,Mickley LA,Schwartz AM,et al.Characterization of adriamycin-resistant human breast cancer cells which display overexpression of a novel resistance-related membrane protein.J Biol Chem,1990,265:10073-10080.
  • 3Doylae LA,Yang W,Abruzzo LV,et al.A multidrug transporter from human MCF-7 breast cancer cells.Proc Natl Acad Sci U S A,1998,95:15665-15670.
  • 4Xu J,Liu Y,Yang Y,et al.Characterization of oligomeric human half-ABC transporter ATP-binding cassette G2.J Biol Chem,2004,279:19781-19789.
  • 5Albermann N,Schmitz-Winnenthal FH,Zgraggen K,et al.Expression of the drug transporters MDR1/ABCB1,MRP1/ABCC1,MRP2/ABCC2,BCRP/ABCG2,and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver.Biochem Pharmacol,2005,70:949-958.
  • 6Mao Q,Unadkat JD.Role of the breast cancer resistance protein(ABCG2) in drug transport.AAPS J,2005,7:118-133.
  • 7Abbott BL,Colapietro AM,Barmes Y,et al.Low levels of ABCG2expression in adult AML blast samples.Blood,2002,100:4594-4601.
  • 8Uggla B,Stahl E,Wagsater D,et al.BCRP mRNA expression v.clinical outcome in 40 adult AML patients.Leuk Res,2005,29:141-146.
  • 9Imai Y,Nakane M,Kage K,et al.C421A polymophism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance.Mol Cancer Ther,2002,1:611-616.
  • 10Zhang S,Yang X,Morris ME.Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport.Mol Pharmacol,2004,65:1208-1216.

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