正常体重指数成年人中心性肥胖对代谢综合征其他组分聚集性的影响

Influence of central obesity on clustering of other risk variables on metabolic syndrome amongadults with normal body mass index

目的探讨正常体重指数（BMI）人群中心性肥胖对代谢综合征（MS）其他组分聚集性的影响。方法采用随机整群抽样的方法，对黑龙江省兰西县平山镇〉35岁并在当地居住5年以上的农村居民进行体格检查，选取正常体重（BMI=18．5-24．9kg／m2）人群作为研究对象，并进行问卷调查和采集空腹静脉血标本。数据分析采用z检验、协方差分析和多因素非条件logistic回归模型。结果（1）调查共抽取平山镇农村正常体重居民1821人，其中男性844人，女性977人。MS患病率为8．68％，中心性肥胖患病率为15．87％，MS及中心性肥胖患病率均是男性低于女性（MS：3．32％vs13．31％；中心性肥胖：5．57％vs．24．77％，均P〈0．001）。（2）MS其他组分（血压、血糖、血脂）聚集的检出率为36．02％，男性为34．12％、女性为37．67％；在MS其他组分检出率上，男女性中心性肥胖患者所有指标检出率均高于正常者。（3）协方差分析显示，男性和女性的腰围指标都随着MS其他组分聚集数目的增加而增加（均P〈0．001）。（4）多因素非条件logistic回归分析显示，中心性肥胖是MS其他组分聚集的危险因素。结论控制正常BMl人群的腰围水平对于MS和心血管疾病的预防是重要的措施。

Objective To study the influence of central obesity on clustering of other metabolic syndrome （MS） risk variables among adults with normal body mass index. Methods Through cluster multistage and random sampling methods, local people aged ~35 years old with normal body mass index （BMI=18.5-24.9 kg/m2） in Lanxi country were selected. Overnight fasting blood specimens of these people were collected. Chi-square test, analysis of covariance, and logistic regression analyses were performed. Results （1） 1821 residents were surveyed including 844 male and 977 female subjects. The overall prevalence of MS was 8.68% and the overall prevalence of central obesity was 15.87%. Both prevalence rates of the two diseases appeared to be lower in males than in females（MS： 3.32% vs. 13.31% ; center obesity： 5.57% vs. 24.77%, all P＇〈0.001）. （2） The overall positive rate of clustering on other MS risk variable was 36.02%, with 34.12% in males and 37.67% in females. Comparing the subjects who did not have central obesity, those subjects wth central obesity had higher positive rate in other MS risk variables. （3） Data from analysis of covariance showed that the level of waist circumference appeared an upward trend along with the count of other MS risk variables （all P（0.001 ）. （4） Data from multivariable logistic regression analysis showed that central obesity was a risk factor on clustering of other MS risk variables. Conclusion Control the level of waist circumference among normal body mass index was an effective method in preventing metabolic syndrome and cardiovascular disease in adults.