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对比等效剂量的舒芬太尼和瑞芬太尼对丙泊酚注射痛和插管反应的抑制作用 被引量:3

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摘要 目的 临床对比等效剂量的舒芬太尼和瑞芬太尼对丙泊酚注射痛和插管反应的抑制作用.方法 选30例需全麻气管插管乳腺手术病人(ASAⅠ-Ⅱ,年龄18~65岁,体重50~70kg)随机分为两组,舒芬太尼-丙泊酚靶控输注组(S组)和瑞芬太尼-丙泊酚靶控输注组(R组),每组各15例.舒芬太尼0.4ng/mL,瑞芬太尼4ng/mL,丙泊酚4μg/mL,罗库溴铵0.6mg/kg,分别记录两组开始注射丙泊酚时的注射痛,入室(baseline),置入喉镜气管插管前(T0),插管后1min (T1),插管后3min(T3),插管后5min(T5)的收缩压(SBP)、舒张压(DBP)、心率(HR)的变化.结果 在S组插管后1min的心率,动脉收缩压和舒张压均高于基础值.在R组插管后1、3、5min的心率,动脉收缩压和舒张压均显著低于基础值.结论 等效剂量的舒芬太尼的镇痛作用强于瑞芬太尼,但等效剂量的瑞芬太尼抑制插管反应的作用强于舒芬太尼.
出处 《中国血液流变学杂志》 CAS 2012年第1期82-83,123,共3页 Chinese Journal of Hemorheology
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同被引文献37

  • 1王琛,王国林.丙泊酚注射痛的机制及预防[J].医学综述,2006,12(2):106-108. 被引量:34
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