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含JmjC结构域的组蛋白去甲基化酶和调控细胞G1／S期转换的基因之间的关系在癌症发病机制中的作用 被引量：1

Roles of relationships between histone demethylase containing Jumonji C domain and genes which regulate G1-S phase transition in tumorigenesis
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摘要 含有JumonjiC结构域的组蛋白去甲基化酶（JHDM）可调控多种基因的转录，影响细胞周期进程，参与癌症发生。本文就JHDM和调控细胞由DNA合成前期向DNA合成期转换的基因的关系作一综述。 Several histone demethylases containing Jumonji C domain （JHDM） have been implicated in tumorigenesis arising from the trancription of the encoding genes and cell cycle control. The relationship between JHDM and the genes which regulate the G1-S phase transition is reviewed in this paper.
作者 马丹 赵洪文
机构地区 中国医科大学附属第一医院呼吸疾病研究所 中国医科大学附属第四医院呼吸内科
出处 《国际呼吸杂志》 2012年第8期624-627,共4页 International Journal of Respiration
基金 国家自然科学基金资助项目（30770956）
关键词 JUMONJI C结构域 组蛋白去甲基化酶 细胞周期 G1/S期转换 J umonji C domain H istone demethylase Cell cycle G1-S transition
分类号 R346 [医药卫生—基础医学]
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参考文献22

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二级参考文献20

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国际呼吸杂志
2012年 第8期

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