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脂肪肝合并腹型肥胖患者抵抗素与胰岛素抵抗关系 被引量:8

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摘要 抵抗素(resistin)是2001年由Steppan等〔1〕发现的一种新的脂肪细胞因子,可作用于肝脏、脂肪等胰岛素靶器官,通过影响胰岛素信号的转导及代谢相关酶的转录而影响糖、脂代谢,参与机体的能量调节。非酒精性脂肪肝病(nonalcoholic fatty liver disease,NAFLD)是一种常见的肝脏疾病,其发病机制目前尚不完全清楚,可能与胰岛素抵抗(insulin resistant,IR)、腹型肥胖、脂肪细胞因子等因素相关。本研究于2008年12月对安徽医科大学第一附属医院健康体检人群中单纯NAFLD患者51例、NAFLD合并腹型肥胖者75例及健康者71例进行研究,旨在通过检测NAFLD、NAFLD合并腹型肥胖患者血清抵抗素水平,分析其与IR及腹型肥胖的关系。现报告如下。
出处 《中国公共卫生》 CAS CSCD 北大核心 2012年第5期687-688,共2页 Chinese Journal of Public Health
基金 安徽省自然科学基金(11040606M200)
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参考文献9

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二级参考文献11

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