流动注射抑制化学发光法快速测定婴幼儿奶瓶中的双酚A

Rapid Determination of Bisphenol A in Nursing Bottles by Flow Injection Inhibitory Chemiluminescence Analysis

建立一种快速测定婴幼儿奶瓶双酚A含量的新型分析方法。以婴幼儿奶瓶为样品,超声波浸提后,用固相萃取柱萃取富集,利用鲁米诺-Cr3+-H2O2流动注射化学发光体系进行测定。结果表明:双酚A对该体系具有抑制发光作用,线性范围为2.0×10-9～1.0×10-5mol/L,检出限为4.6×10-10mol/L,加标回收率为95.4%～106.8%,相对标准偏差小于4%(n=7)。该法与国标法相比,具有灵敏度高、操作简便、测定快速、成本低廉、利于普及推广等优点,分析结果令人满意。

In order to establish a new rapid method for determining bisphenol A（BPA） in nursing bottles,cut pieces of nursing bottles were extracted with high-purity water under ultrasonic assistance,and the extracted analyte was enriched by solid phase extraction and determined using a uminol-H2O2-Cr chemiluminescence system.The esults showed that the chemiluminescence system was inhibited by BPA.An excellent linear relationship was observed in the range of 2.0 × 10-9-1.0 × 10-5 mol/L.The detection limit was 4.6 × 10-10 mol/L.The average spike recoveries of BPA in 5 types of commercial samples were in the range of 95.4%-106.8%,and the relative standard deviations for 7 parallel determinations were all less than 4%.The method had the advantages of sensitivity,simplicity,rapidity,low cost and accuracy over the Chinese national standard method,thus being worth promoting and popularizing.