多药耐药菌医院感染的监测与控制

Monitoring and control of nosocomial infection caused by multidrug-resistant bacteria

目的了解住院患者多药耐药菌(MDROs)医院感染状况,为及时采取有效的预防控制措施提供依据。方法采用前瞻性调查方法,对2009-2010年临床标本检出多药耐药菌的住院患者进行目标性监测。结果医院感染例次感染率为20.4%,2009、2010年例次感染率分别为22.4%和18.8%;以下呼吸道感染占首位,科室分布最多的为ICU。结论多药耐药菌医院感染发生率高,临床医师应高度重视,积极治疗原发病,控制感染危险因素,减少医院感染的发生。

OBJECTIVE To understand the status of the nosocomial infections caused by multidrug-resistant organism（MDRO）in inpatients,and to provide evidence for the effective control measures.METHODS Using the prospective study method,we enrolled the inpatients with MDRO isolated from clinical samples from 2009 to 2010 by applying the targeted monitoring.RESULTS The incidence of nosocomial infections was 20.4%,and the infection rates in 2009 and 2010 were 22.4% and 18.8%,respectively;lower respiratory tract infection took the first place,and most of the isolates distributed in ICU.CONCLUSION The incidence rate of nosocomial infections caused by MDRO is high,the clinicians should pay special attention to these patients,it should strengthen the treatment of primary diseases and control the risk factors for the infections so as to reduce the nosocomial infections.