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乳腺癌彩色多普勒血流表现与术后组织中血管内皮生长因子和血管密度的关系 被引量:5

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摘要 目的探讨术前应用三维彩色多普勒超声对乳腺癌的诊断价值,关注其声像与乳腺癌中血管内皮生长因子(VEGF)和血管密度(MVD)的关系。方法收集87例乳腺癌患者术前三维彩色多普勒超声资料,观察乳腺癌超声特征,并探讨血流分级、血流指数(Vmax)与术后VEGF与CD34标记肿瘤中血管密度(MVD)的关系。结果 87例患者,超声诊断81例与术后病理符合,符合率为93.10%。彩色多普勒检测乳腺癌中血流分级、Vmax与肿瘤VEGF表达阳性率、MVD表达量均与肿瘤直径、淋巴结转移及Ki67表达有关,相关分析显示血流分级、Vmax、VEGF阳性率及MVD均呈正相关性。结论三维彩色多普勒超声检测血流分级对乳腺癌具有较高的术前诊断价值,术前检测血流分级、Vmax可以反映乳腺癌MVD情况,可能对于术前判断肿瘤预后和指导治疗有一定价值。
作者 周历安
出处 《中国老年学杂志》 CAS CSCD 北大核心 2012年第9期1831-1832,共2页 Chinese Journal of Gerontology
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