1Xue YH,Zhang XF,Dong QZ,et al.Thrombin is a therapeutic target for metastatic osteopontin-positive hepatocellular carcinoma(J).Hepatology,2010;52(6):2012-22.
2García PS,Gulati A,Levy JH.The role of thrombin and protease-activated receptors in pain mechanisms(J).Thromb Haemost,2010;103(6):1145-51.
3Maki J,Hirano M,Hoka S,et al.Involvement of reactive oxygen species in thrombin-induced pulmonary vasoconstriction(J).Am J Respir Crit Care Med,2010;182(11):1435-44.
4Alexander SP,Mathie A,Peters JA.Guide to Receptors and Channels(GRAC),3rd edition(J).Br J Pharmacol,2008;153(Suppl.2):1-209.
5Offermanns S.Activation of platelet function through G protein-coupled receptors(J).Circ Res,2006;99(12):1293-304.
6Russell FA,Zhan S,Dumas A,et al.The pronociceptive effect of protein-ase-activated receptor-4 stimulation in rat knee joints is dependent on mast cell activation(J).Pain,2011;152(2):354-60.
9Tsopanoglou NE,Maragoudakis ME.On the mechanism of thrombin-in-duced angiogenesis.Potentiation of vascular endothelial growth factor ac-tivity on endothelial cells by up-regulation of its receptors(J).J Biol Chem,1999;274(34):23969-76.
4Fukuhara A, Matsuda M, Nishizawa M ,et al.Visfatin:a pro- tein secreted by visceral fat that mimics the effects of in- sulin[J].2005,307 (5708) : 426-430.