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胃肠道肿瘤患者的营养风险筛查及营养状况评价 被引量:76

Nutritional risk screening and nutrition assessment for gastrointestinal cancer patients
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摘要 目的探讨胃肠道肿瘤患者的营养状况,为营养治疗的选择提供依据。方法选取2010年6月至2011年12月期间中山大学附属第六医院收治的453例胃肠道肿瘤患者作为研究对象,其中胃癌156例,结肠癌117例,直肠癌180例。应用营养风险筛查2002(NRS2002)进行营养风险评分;多频生物电阻抗分析仪测定机体组分;空腹抽血测定白蛋白(Alb)、前白蛋白(PA)、转铁蛋白(Tf)和视黄醇结合蛋白(RBP)4项营养指标以及红细胞(RBC)、血红蛋白(Hb)和红细胞比容(Hct)3项血液指标。结果NRS2002评分结果显示,总评分在3分以上者在胃癌、结肠癌和直肠癌中所占的比例分别为70.5%(110/156)、53.8%(63/117)和46.7%(86/180),胃癌明显高于结肠癌和直肠癌(/9〈0.05);营养受损评分1分以上者的比例胃癌高于结肠癌和直肠癌(P〈0.05);而疾病评分2分以上者的比例却低于结肠癌和直肠癌(P〈O.05)。胃癌患者体质量指数、肥胖度、脂肪含量、脂肪百分数、手臂围度均明显低于结肠癌和直肠癌,而蛋白质百分比、肌肉百分比、手臂肌肉百分数、细胞质量百分数却明显高于结肠癌和直肠癌(P〈0.05)。胃癌和结肠癌患者中Alb、PA、Tf、RBC、Hb及Hct低于正常值的比例均高于直肠癌(P〈0.05)。结论胃癌患者易出现脂肪的丢失.存在营养风险及营养不良的概率高于结肠癌和直肠癌。联合人体组分分析及实验室检查能够更全面地评定胃肠道肿瘤患者的营养状况.与NRS2002评分相结合,可作为营养治疗方案的选择依据。 Objective To investigate the nutritional status, and provide evidence for nutritional treatment option. Methods A total of 452 patients with gastrointestinal cancer were selected, including 156 gastric cancer,ll7 colon cancer, and 180 rectal cancer. The nutritional risk screening 2002 (NRS2002) was applied to grade the nutritional risk. A multi-frequency bioelectrical impedance analysis was used to measure the patients' body composition. Albumin (Alb), prealbumin (PA), transferring(Tf), retinol binding protein (RBP), red blood cell (RBC), hemoglobin (Hb), haematocrit (Het) were measured after fasting. Results The rate of patients with NRS2002 score more than 3 was 70.5% (110/156) for gastric cancer, 53.8% (63/117) for colon cancer, and 46.7% (86/180) for rectal cancer. The score for impaired nutritional status more than 1 for gastric cancer was higher than that for colorectal cancer(P〈0.05), while patients with disease score more than 2 was less for gastric cancer (t)〈0.05). Body mass index (BMI), obesity degree, fat content, fat percentage, and arm circumference were lower in gastric cancer patients as compared to colorectal cancer patients (P〈0.05); but protein
出处 《中华胃肠外科杂志》 CAS 2012年第5期460-463,共4页 Chinese Journal of Gastrointestinal Surgery
基金 广东省科技计划项目(20108031500009)
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