天津市老年人膝关节骨关节炎流行病学调查

Epidemiological investigation of knee osteoarthritis among the elderly in Tianjin

目的了解天津市老年人膝关节骨关节炎（0A）的患病情况及相关危险因素。方法采用亚太地区风湿病协会联合会社区控制风湿病规划调查方法，应用《膝骨关节炎危险因素调查表》于2010年1月至2011年6月对天津市部分老年人共2038例进行调查。结果天津市老年人膝痛和膝关节OA的患病率分别为23．1％和21．7％。女性患病率为27．6％高于男性的16．1％（X^2=46．893，P〈0．001），且随年龄增长患病率增高（X^2=764．34，P〈0．001）。膝关节0A组BMI（25．4±3．3）kg／m^2高于非膝关节0A组（23．8±2．9）kg／m^2（t=7．944，P〈0．001）。女性膝关节OA患者绝经年龄（50．2±3．7）岁早于非膝关节0A患者（52，8±4．1）岁（t=7．665，P〈0．001）。Logistic回归分析显示年龄、性别、BMI、绝经年龄是膝关节OA的危险因素，进食蔬菜是膝关节OA的保护因素。结论年龄、女性、超重是膝关节0A的危险因素。

Objective To explore the among the elderly in Tianjin. Methods January 2010 to June 2011 according to identification of risk factors for knee OA. prevalence and risk factors of knee osteoarthritis （OA） Totally 2038 elderly in Tianjin were investigated from protocol of APLA-COPCORD Core Questionnaire to Results The prevalence rates of knee pain and knee OA were 23.1% and 21.7%, respectively. Knee OA appeared much frequently in women than men （27.6%% vs. 16.1%, ）%2 =46. 893, P〈0. 001） in the trend of increase with aging（x2= 764.34, P〈 0. 001）. BMI in knee OA group [（25.4%3.3） kg/m2]was significantly higher than in non-knee OA group [（23.8±2.9） kg/m2] , （t=7. 944,P〈0. 001）. Menopause age in female knee OA group was younger than in female nonknee OA group [（50.24-3.7） years vs. （52.8＋4.1） years, t=7.665, P〈0. 001]. Binary logistie regression revealed that age, sex, BMI and age of menopause were risk factors of knee OA, and eating vegetable might prevent from osteoarthritis, whereas there were no significantly association between knee OA and the other factors such as smoking and drinking. Conclusions Age, female and overweight are identified as risk factors of knee OA.