期刊文献+

骨形态发生蛋白在椎间盘退变过程中作用及相关机制的研究进展

Advances of the role and mechanism of the bone morphogenetic protein in the intervertebral disc degeneration
下载PDF
导出
摘要 骨形态发生蛋白bone morphogenetic proteins.BMPs)作为促进植骨融合的经典生长因子为大众熟知,近年来BMPs在椎间盘退变过程中的作用及相关机制被广泛关注和研究。BMP-2、-5、-6、-8、-9和-14对软骨细胞的作用被相继发现。越来越多的研究学者认为,
作者 陈智 沈洪兴
出处 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2012年第5期458-461,共4页 Chinese Journal of Spine and Spinal Cord
  • 相关文献

参考文献1

二级参考文献18

  • 1Masuda K, Oegema TR, An HS. Growth factor and treatment of intervertebral disc degeneration. Spine 2004, 29:2757-2769
  • 2Thompson JP, Oegema TR, Bradford DS. Stimulation of mature canine intervertebral disc by growth factor. Spine 1991, 16:253-260
  • 3Masuda K, Takegami K, An H, Kumano E Chiba K, Andersson GB, Schmid T et al. Recombinant osteogenic protein-1 upregulates extracellular matrix metabolism by rabbit annulus fibrosus and nucleus pulposus cells cultured in alginate beads. J Orthop Res 2003, 21:922-930
  • 4Yoon ST, Kim KS, Li J, Park JS, Akamaru T, Elmer WA, Hutton, WC. The effect of bone morphogenetic protein-2 on rat intervertebral disc cells in vitro.Spine 2003, 28:1773-1780
  • 5Li J, Yoon ST, Hatton WC. Effect of bone morphogenetic protein-2 (BMP-2) on matrix production, other BMPs, and BMP receptors in rat intervertebral disc cells. J Spinal Disord Tech 2004, 17:423--428
  • 6Okuda S, Myoui A, Ariga K, Nakase T, Yonenobu K, Yoshikawa H.Mechanisms of age-related decline in insulin-like growth factor-Ⅰ dependent proteoglycan synthesis in rat intervertebral disc cells. Spine 2001, 26:2421-2426
  • 7Matsumoto T, An H, Thonar E, Andersson G, Masuda K. Effect of osteogenic protein-1 on the metabolism of proteoglycan of intervertebral disc cells in aging. Orthop Res Soc Trans 2002, 27:826
  • 8Kim YJ, Sah RL, Doong JY, Grodzinsky AJ. Fluorometric assay of DNA in cartilage explants using Hoechst 33258. Anal Biochem 1988, 174:168-176
  • 9Farndale RW, Buttle D J, Barrett AJ. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta 1986, 883:173-177
  • 10Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2^-△△Ct method. Methods 2001, 25: 402-408

共引文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部