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聚乙二醇化干扰素α-2a治疗慢性乙型肝炎临床观察

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摘要 目的观察聚乙二醇化干扰素α-2a治疗慢性乙型肝炎的临床疗效。方法选取安阳市第五人民医院收治的48例慢性乙型肝炎患者为研究对象,给予聚乙二醇化干扰素α-2a皮下注射,对比观察所有患者治疗前后相关指标变化情况。结果与治疗前相比,所有患者治疗后肝组织坏死及炎症程度均明显减轻(P<0.01),血清HBV DNA水平治疗后较治疗前明显下降(P<0.01),治疗后HBeAg血清转换率为50%(24/48)。结论聚乙二醇化干扰素α-2a可显著降低慢性乙肝患者血清中HBV DNA水平,有效改善肝组织病变情况。
作者 谢东文
出处 《医药论坛杂志》 2012年第4期99-100,共2页 Journal of Medical Forum
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