地塞米松不同给药方式治疗突发性聋的疗效观察

The effect of dexamethasone in different application on treatment of sudden sensorineural hearing loss

目的:探讨地塞米松不同给药方式治疗突发性聋的疗效。方法:回顾性分析100例突发性聋患者,将其分为2组,A组(50例)全身静脉注射地塞米松,B组(50例)鼓室内注射地塞米松。结果:A、B组治疗总有效率分别为66%、68%,差异无统计学意义(P>0.05)。结论:不管全身方式给药,还是局部鼓室给药,使用地塞米松治疗突发性聋的疗效相仿。

Objective：To investigate the effect of dexamethasone through different methods of administration in treatment of sudden sensorineural hearing loss. Method：One hundred cases of sudden sensorineural hearing loss were retrospectively studied, in which patients were divided into 2 groups as A and B. The cases were treated with dexamethasone intravenous injection in A group and intratympanie application in B group. Result.. The total effec- tive rate was 66.00G in A group and 68.00% in B group. The difference between the total effective rate in group A and B did not reach significance in statisties（P〉0.05）. Conclusion： The effect of dexamethasone intravenous injection and intratympanie application on treatment of sudden sensorineural hearing loss has no difference.