FOLFIRI方案治疗转移性结直肠癌的护理

Nursing for Metastatic Colorectal Cancer Patients Treated with FOLFIRI Regimen

目的:探讨FOLFIRI方案治疗转移性结直肠癌的副反应的有效护理方法。方法:28例转移性结直肠癌的患者,采用FOLFIRI方案化疗,给予心理护理、中心静脉导管护理、急性乙酰胆碱能综合征的护理、迟发性腹泻护理及健康教育等护理措施。结果:出现急性乙酰胆碱能综合征7例,迟发性腹泻6例,骨髓抑制5例,恶心、呕吐18例,经及时对症处理和实施综合护理,28例患者全部顺利完成治疗。结论:对接受FOLFIRI方案治疗转移性结直肠癌的患者,及时给予有效的护理措施,可减少副反应的发生,从而使患者顺利完成治疗,提高生活质量。

Objective： To investigate effective nursing methods for side effects induced by FOLFIRI regimen in metastatic colorectal cancer patients. Methods： Twenty-eight pathologically diagnosed metastatic colorectal cancer patients were treated with FOLFIRI regimen. Nursing interventions such as mental nursing, central venous catheter nursing, acute cholinergic syndrome nursing, delayed-onset diarrhea nursing and health education were concucted. Results： Acute cholinergic syndrome occurred in 7 cases , de- layed-onset diarrhea in 6 cases, myelosupression in 5 cases and nausea and/or vomiting in 18 cases. After timely symptomatic treat- merits and comprehensive nursing interventions, all the 28 cases had successfully completed chemotherapy. Conclusions ： For metastat- ic colorectal cancer patients treated with FOLFIRI chemotherapy, timely and effective nursing interventions can reduce side-effects as well as insure successful completion of chemotherapy and improve the life quality of patients.