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聚乙二醇干扰素α-2a与利巴韦林对慢性丙型肝炎患者血清脂联素浓度的影响 被引量：6

Changes of the serum adiponectin during treatment with peginterfemn α-2a and ribavirin for chronic hepatitis C
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摘要 本研究通过观察聚乙二醇干扰素（pegylated interferon，PegIFN）α-2a联合利巴韦林（ribavirin，RBV）治疗慢性丙型肝炎过程中患者血清脂联素浓度的变化情况，进一步探讨HCV和血清脂联素水平的关系。
作者 黄平 杨永峰 熊清芳 钟艳丹
机构地区 东南大学附属第二医院肝病科
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2012年第5期394-395,共2页 Chinese Journal of Hepatology
基金 南京市医学科技发展项目青年科技人才启动项目（QYK09154） 江苏省自然科学基金（BK2011100）
关键词 干扰素类 肝炎 丙型 慢性 脂联素 Interferons Hepatitis C, chronic Adiponectin
分类号 R512.63 [医药卫生—内科学]
  • 相关文献

参考文献6

  • 1丙型肝炎防治指南[J].临床肝胆病杂志,2004,20(4):197-203. 被引量：735
  • 2Hu KQ,Vierling JM,Redeker AG.Viral, host and interferon-related factors modulating the effect of interferon therapy for hepatitis C virus infection. J Vtral Hepat, 2001, 8: 1-18.
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  • 6Meng QH, Duan ZH, Lin ZH, et aL Serum level of adiponectin correlated with gender and genotype in patients with chronic hepatitis C. Dig Dis Sci, 2009, 54:1120-1127.

二级参考文献15

  • 1Camma C, Bruno S, Schepis F, et al. Retreatment with interferon plus ribavirin of chronic hepatitis C non- responders to interferon monotherapy: a meta- analysis of individual patient data[ J ]. Gut, 2002,51:864-869.
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共引文献734

同被引文献50

  • 1马丽娜,陈新月,陈杰,沈成利,汪俊韬.聚乙二醇干扰素治疗慢性丙型肝炎临床疗效、影响因素及安全性分析(附89例临床分析)[J].中华实验和临床病毒学杂志,2006,20(2):42-45. 被引量：29
  • 2Laml T. Sehulz-Lobmeyr I, Obruca A, et al . Premature o- varian failure: etiology and prospects [J]. Gynecol Endocrinol, 2000, 14(4) : 292-302.
  • 3Trepanowski JF, Kabir MM, Alleman RJ, et al. A 21-day Daniel fast with or without krill oil supplementation improves anthropometric parameters and the cardiometabolic profile in men and women[J]. Nutr Metab (Lond) ,2012, 9(1):82.
  • 4Shi K, Ugi S, Shimizu S, et al. Membrane localization of protein tyrosine phosphatase 1B is essential for its activation of sterol regulatory element-binding protein-1 gene expression [J]. Biochem Biophys Res Commun ,2007, 363(3) :626-632.
  • 5Ugi S, Shi K, Nishio Y, et al. Membrane localization of protein-tyrosine pbosphatase 1B is essential for its activation of sterol regulatory element- binding protein-1 gene expres- sion and consequent hypertriglyceridaemia [J]. J Biochem , 2009, 146(4) :541-547.
  • 6Lee W, Yoon G, Hwang YR, et al. Anti obesity and hypo lipidemic effects of Rheum undulatum in high-fat diet-fed C57BL/6 mice through protein tyrosine phosphatase 1B inhi- bition [J]. BMB Rep ,2012, 45(3):141-146.
  • 7Kaszubska W, Falls HD, Schaefer VG, et al . Protein tyro- sine phosphatase 1B negatively regulates leptin signaling in a hypothalamie cell line [J]. Mol Cell Endocrinol , 2002, 195 (12):109 -118.
  • 8Tsou RC, Zimmer DJ, De Jonghe BC, et al . Deficiency of PTPIB in leptin receptor-expressing neurons leads to de- creased body weight and adiposity in mice [ J ]. Endocrinology ,2012, 153(9) :4227-4237.
  • 9Cuevas JM, C onzalez M,Torres-PuenreM,et al.The role of Positive Seleetion in hepatitis C vims[J].InfeetioncenetEvol, 2000,9(5):860-866.
  • 10Poynard T, McHutchimJ, MannsM,et al.lrnPact of Pegylatedinte-denm Alfa- 2aane Ifibavifinonli Verfibrosisin Patients with clironiche PatitisC [J]. Gastroenterology, 2002,122(5):1303.

引证文献6

二级引证文献30

中华肝脏病杂志
2012年 第5期

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