子宫内膜异位症腹腔镜保守性手术后复发的影响因素研究

Correlative factors analysis of recurrence of endometriosis after conservative laparoscopic surgery

目的探讨子宫内膜异位症腹腔镜保守性手术后复发的影响因素。方法回顾性分析该院行腹腔镜保守性手术治疗的126例EMs患者的临床资料并随访3年,对可能影响复发的相关因素(年龄、盆腔病变位置、既往有无EMs手术史、既往腹腔镜手术史、R-AFS分期、术前CA125水平、术后克罗米酚促排卵治疗及术后GnRH-a治疗)进行分析。结果盆腔病变位置、有无EMs手术史、R-AFS分期、术前CA125水平、有无术后克罗米酚促排卵治疗及术后GnRH-a治疗等6个因素与术后复发有关系(P<0.05);Logistic回归分析发现既往有盆腔病变位置、无EMs手术史、R-AFS分期、术后克罗米酚促排卵治疗及术后GnRH-a治疗是影响腹腔镜保守性治疗后患者复发的独立因素。结论既往有无EMs手术史、盆腔病变位置、R-AFS分期、术后克罗米酚促排卵治疗及术后GnRH-a治疗是影响EMs患者行腹腔镜保守性手术后复发的独立因素。

[Objective] To explore the correlative factors with recurrence of endometriosis after conservative laparoscopic surgery.[Methods] 126 patients of endometriosis were treated with laparoscopic surgery and then followed up for 3 years.126 patients were analyzed retrospectively.The factors measured included：age,side of endometrioma,history of operation for endometriosis,history of laparoscopic surgery,type of R-AFS,serum CA125 level,post-operative GnRH-a therapy,post-operative Clomiphene therapy.[Results] The recurrence of endometriosis after conservative laparoscopic surgery was related to side of endometrioma,history of operation for endometriosis,type of R-AFS,CA125 level,post-operative GnRH-a therapy,post-operative Clomiphene therapy.The related factors by Logistic analysis were as follows：side of endometrioma,history of operation for endometriosis,type of R-AFS,post-operative GnRH-a therapy,post-operative Clomiphene therapy.[Conclusions] The correlative factors for recurrence of endometriosis after conservative laparoscopic surgery are side of endometrioma,history of operation for endometriosis,type of R-AFS,post-operative GnRH-a therapy,post-operative Clomiphene therapy.