摘要
A组轮状病毒是导致全球婴幼儿重症腹泻的最主要病因,其疾病负担巨大。已有研究证实,卫生状况的改善对轮状病毒腹泻的控制效果甚微,疫苗则是控制轮状病毒腹泻最有效的公共卫生干预措施。目前3种轮状病毒疫苗已在全球100多个国家及地区投入使用,并纳入部分国家的儿童计划免疫程序。本文简要综述人A组轮状病毒疫苗的研究进展,以期对我国轮状病毒疫苗的使用和推广提供借鉴。
Group A rotavirus （RV） is the leading cause of severe diarrhea disease in infants and young children worldwide, which causes a high desease burden. Studies have indicated that further improvements in hygiene are unlikely to prevent the disease. Rotavirus vaccines are the most effective public health interventions for controlling rotavirus diarrhea. Currently there are 3 different brands of rotavirus vaccines put into use globally in more than 100 countries and regions, and have been included in some countries＇childhood vaccination programs. This review briefly introduces the development status of Group A rotavirus vaccines, providing a reference for application and further promotion of rotavirus vaccines in our country.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2012年第10期1088-1092,共5页
Chinese Journal of New Drugs
关键词
人轮状病毒
腹泻
疫苗
human rotavirus
diarrhoea
vaccine
