带状疱疹疫苗的研究现状及发展趋势

Research status and development trends of herpes zoster vaccine

水痘-带状疱疹病毒原发感染为水痘,再度被激活则引起带状疱疹(HZ)。近年来,随着国内人口结构的老龄化趋势日益加重,HZ的发病率有明显上升的趋势,且引起的后遗神经痛使用抗病毒药物治疗无明显疗效。HZ的防治现已成为重要的公共卫生问题。采用疫苗预防HZ已经越来越被社会所接受。本文就该病原体及其疫苗方面的研究现状及进展作一综述。

Original infection of varicella-zoster virus can induce varicella and then herpes when the virus is activated again. In recent years, with the progress of aging of domestic population, the incidence rate of herpes is increasing apparently, and there is no apparent therapeutic effect to treat post-herpetic neuralgia caused by herpes with antiviral drugs. Therefore, the prevention and therapy of herpes has been attached more and more importance for it has become an important public hygiene issue. The prevention of herpes with vaccine has been accepted by the society widely. In this article, we summarized the causative agent of herpes and the current situation of research and development of vaccine research.