期刊文献+

骨髓间充质干细胞治疗椎间盘退变研究进展 被引量:4

下载PDF
导出
摘要 骨髓间充质干细胞(BMSC)具有多向分化能力、免疫原性和免疫调节性等特点,可大量获取。许多学者对BMSC特性进行实验研究,并诱导其在体外和体内向椎间盘样细胞分化,已有大量研究成果证实将BMSC用于治疗椎间盘退变的可行性。近年也有将BMSC移植入椎间盘退变患者并获得延缓椎间盘退变效果的临床报道。该文就BMSC治疗椎间盘退变的基础研究和临床研究作一综述。
出处 《国际骨科学杂志》 2012年第3期181-183,185,共4页 International Journal of Orthopaedics
  • 相关文献

参考文献38

  • 1Colter DC, Class R, DiGirolamo CM, et al. Rapid expansion of rycling stem cells in cultur of plastic-adherent ceils from human bone rmrmw. Proc Nail Acad Sd USA, 2300, 97(7) :3213-3218.
  • 2Tamir A, Petrocelli T, Stetler K, et al. Stem cell factor inhibits erythroid differentiation by rrtxtulating the activity of Gl-cydirrdetxdent kinase complexes: a role for p27 in erythroid differentiation coupled G1 arrest. Cell Growth Differ, 2000, 11(5):269-277.
  • 3Rubio D, Garda-Castro J, Martin IVY;, et al. Spontaneous human adult stem cell transforrmtio Cancer Res, 2005, 65(8):3035-3039.
  • 4Rosland GV, Svendsen A, Torsvik A, et al. Long-terra cultures of bone marrow-derived human mesenchymal stun ceils frequently undergo spontaneous malignant transforrmfion. Cancer Res, 2309, 69(13) :5331-5339.
  • 5Pittenger MF, MacKay AM, Beck 5K;, et al. Multilineae potential of adult huroan mesenchymal stem cells Science, 1999, 284(5411):143-147.
  • 6Lee KD, Kuo TK, Whang-Peng J, et al. In vitro hepatic differentiation of hurmn mesenchymal stern cells. Hepatology, 2004,40(6):1275-1284.
  • 7Arthur A, Zannettino A, Gronthos S. The therapeutic applications of multipotential rnesenchymal/stromal stem cells in skeletal tissue repair. J Cell Physiol, 2(109, 218(2) :237-245.
  • 8Vacanti V, Kong E, Suzuki G, et al. Phenotypic changes of adult porcine mesenchyrnal stem cells induced by prolonged passaging in culture. J Cell Physiol, 2005, 205(2):194-201.
  • 9le Blanc K, Tammik C, Rosendahl K, et al. HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells Exp Hernatol, 2003, 31 (10) :890- 896.
  • 10Chan JL, Tang KC, Patel AP, et al. Antigen-presenting property of mesenehymal stem cells occurs during a narrow window at low levels of interferon-garrana. Blood, 2006, 107(12) :4817-4824.

同被引文献17

引证文献4

二级引证文献29

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部