中西医结合治疗高催乳素血症不孕症临床分析

Clinical Analysis of Traditional Chinese and Western Medicine Treatment on Infertility Patients with Hyperprolactinemia

目的:观察中西医治疗高催乳素血症不孕症患者43例的的临床疗效。方法:将86例高催乳素不孕症患者,随机分为对照组、治疗组两组。对照组43例患者给予溴隐亭治疗,治疗组加服自拟疏肝补肾汤,连服3个月。观察两组患者的临床疗效、性激素[包括催乳素(PRL)、黄体生成素(LH)、卵泡刺激素(FSH)、雌二醇(E2)、孕酮(P)、睾酮(T)]水平,临床症状积分及妊娠情况等。结果:治疗组、对照组的临床疗效95.3%、79.1%;治疗后两组均可降低PRL水平,提高E2、P水平(P>0.05);但治疗组在临床症状改善方面明显优于对照组(P<0.05);治疗组妊娠率显著高于对照组(P<0.05)。结论:中西医治疗高催乳素血症不孕症具有良好的疗效,可改善患者临床症状,提高妊娠率,减少溴隐亭的不良反应,值得临床推广应用。

Objective： To observe the effect of traditional Chinese and western medicine treatment on 43 infertility patients with hyperprolactinemia.Methods：86 patients of infertility with high prolactin were randomly divided into control group and treatment group.43 patients in the control group were given bromocriptine,the treatment group also took liver-soothing and kidney-nourishing decoction for 3 months.The clinical efficacy,sex hormones（including PRL,LH,FSH,E2,P,T）levels,clinical symptom score and pregnancy rate were observed.Results：The clinical efficacy of treatment group and control group were 95.3% and 79.1 %;after treatment the two groups could reduce PRL levels effectively and improve E2,P levels（P0.05）;but in the treatment groups clinical symptoms improvement were better than that in the control group（P0.05）;the pregnancy rate of treatment group was significantly higher than that of the control group（P0.05）.Conclusion：Traditional Chinese and western medicine treatment has good curative effect on infertility patients with hyperprolactinemia and can improve clinical symptoms,increase the pregnancy rate and reduce the adverse effects of bromocriptine.It can be worthy of clinical application.