摘要
:根据化学动力学原理 ,采用经典恒温方法 ,设置 6 5℃ ,75℃ ,85℃ ,95℃共 4个温度和 5个间隔时间 ,测定出百痢停注射液中恩诺沙星的分解反应为一级反应 ,K2 5℃ 为 4.8770× 1 0 -6H-1,t 2 5℃0 .9为 2 .46年 ,其pH值、澄明度和色泽指标在试验期内无显著变化 。
Four reaction temperatures (65,75,85 and 95℃) and five durations of reaction time were adopted in a test with the classical constant temperature method for the stability of Bai Li Ting, an injection developed by this institute with enrofloxacin as its main constituent. The decomposition reaction of enrofloxacin in it was shown to be of one-order kinetics, K 25℃ being 4.8770 x 10 -6 h -1 and t 25℃ 0.9 being 2.64 years. The pH, color and clarity of the injection underwent no marked change during the test time, thus supplying sound basis for evaluating the stability of the injection.
出处
《西南农业大学学报（自然科学版）》
CSCD
2000年第2期137-139,共3页
Journal of Southwest Agricultural University
关键词
百痢停注射液
稳定性
恩诺沙星
经典恒温法
兽药
Bai Li Ting injection
stability
enrofloxacin
classical constant temperature method
