DEXA技术测量体脂含量及其与2型糖尿病代谢指标的相关性

Detection of body fat composition by dual energy X-ray absorptiometry and its relations with metabolic indices of type 2 diabetic patients

目的探讨双能X线吸收法(dual energy X-ray absorptiometry,DEXA)测量体脂分布的价值及其与2型糖尿病代谢相关因素的关系。方法使用DEXA法测量123例2型糖尿病患者及112例正常对照者的体脂分布,与腹型肥胖诊断标准腰围进行一致性检验,探讨其与糖尿病代谢因素的关系。结果躯干脂肪比例与腰围诊断肥胖症具有良好的一致性,诊断切点为>35.56%,可反映胰岛素抵抗(IR),以诊断切点划分的病例组与对照组之间血压、血脂、糖化血红蛋白等指标具有统计学差异。结论 DEXA测量的体脂分布可评价腹型肥胖,肥胖与高血压、胰岛素抵抗、血脂紊乱等肥胖代谢相关因素具有相关性。

Objective To explore the value of dual energy X-ray（DEXA） in detection of body fat composition,and the relationships between body fat composition and metabolic indices of type 2 diabetic patients. Methods DEXA was used to determine the body fat composition in 123 type 2 diabetic patients and 112 normal controls.The consistency between the body fat composition and the standard waistline for abdominal obesity was verified.The correlation between body fat composition and metabolic index was analyzed in type 2 diabetic patients. Results The diagnosis results were consistent between trunk fat tissue（trunk FAT） measured by DEXA and the standard waistline for abdominal obesity.The obese cutoff point was 35.56%.According to the obese cutoff point,the patients and normal controls were respectively divided into two subgroups.Blood pressure,blood lipid and HbA1C were statistically different among four subgroups. Conclusion The trunk FAT measured by DEXA can evaluate the abdominal obesity and reflect IR to a certain degree.Obese is related to the hypertension,insulin resistance and blood fat disorder.