E选择素基因A561C多态性与2型糖尿肾病的相关性研究
被引量:2
摘要
随着人民生活水平日益提高,2型糖尿病发病率不断增加,严重影响我国人民生活质量。糖尿病肾病是2型糖尿病最严重的并发症,是糖尿病患者死亡的常见原因之一。探讨糖尿病肾病的发病机制已经成为一个亟待解决的科学问题。最近的研究表明血清可溶性E-选择素表达的增加与糖尿病的发病密切相关,但E-选择素基因多态性与糖尿病肾病的相关性研究却一直未见报道。
出处
《中国实验诊断学》
2012年第5期904-907,共4页
Chinese Journal of Laboratory Diagnosis
参考文献12
-
1Maric,C.and J.E.Hall,Obesity,metabolic syndrome and diabeticnephropathy[J].Contrib Nephrol,2011,170:p.28.
-
2Najafian,B.,C.E.Alpers,and A.B.Fogo,Pathology of human di-abetic nephropathy[J].Contrib Nephrol,2011,170:p.36.
-
3Bannan,S.,M.W.Mansfield,and P.J.Grant,Soluble vascularcell adhesion molecule-1and E-selectin levels in relation to vascu-lar risk factors and to E-selectin genotype in the first degree rela-tives of NIDDM patients and in NIDDM patients[J].Diabetolo-gia,1998,41(4):p.460.
-
4El-Mesallamy,H.O.,et al.,Adiponectin and E-selectin concen-trations in relation to inflammation in obese type 2diabetic pa-tients with coronary heart disease(s).Minerva Endocrinol,2011.36(3):p.163-70.
-
5Navarro-Gonzalez,J.F.,et al.Inflammatory molecules and path-ways in the pathogenesis of diabetic nephropathy[J].Nat RevNephrol,2011.7(6):p.327.
-
6Ogawa,D.and K.Shikata,[Microinflammation in diabetic ne-phropathy][J].Nihon Jinzo Gakkai Shi,2011.53(7):p.1021.
-
7Jubeli,E.,et al.,E-selectin as a target for drug delivery and mo-lecular imaging[J].J Control Release,2011.
-
8Brorsson,C.and F.Pociot,Genetics of diabetic nephropathy in di-verse ethnic groups[J].Contrib Nephrol,2011.170:p.8.
-
9Abu-Amero,K.K.,et al.E-selectin S128Rpolymorphism and se-vere coronary artery disease in Arabs[J].BMC Med Genet,2006,7:p52.
-
10Navarro-Hernandez,R.E.,et al.sE-Selectin expression andA561Cpolymorphism in relation to rheumatoid arthritis clinicalactivity[J].J Rheumatol,2006.33(10):p1968.
同被引文献22
-
1王翠珍,林丽香,陈刚,庄维特,林苗,温俊平,林庆明.2型糖尿病大鼠肾脏组织氧化应激相关基因的表达[J].海峡预防医学杂志,2005,11(2):3-5. 被引量:5
-
2王银娜,刘惠兰,孙懿,刘群.细胞间黏附分子1基因K469E多态性与2型糖尿病肾病的相关性研究[J].中华肾脏病杂志,2006,22(4):201-204. 被引量:2
-
3诸福棠.实用儿科学[M]{H}北京:人民卫生出版社,2002688.
-
4Wang LJ,Yang YH,Lin YT. Levels of intracellular adhesionmolecule-1 and vascular cell adhesion m0lecule-1 in children withHenoch-Seh,nlein purpura[J].{H}Journal of Microbiology Immunology and Infection,2006.109-113.
-
5David R. Whiting,Leonor Guariguata,Clara Weil,Jonathan Shaw.IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030[J].Diabetes Research and Clinical Practice.2011(3)
-
6Xu Y,Wang L,He J,et al.Prevalence and control of diabetes in Chinese adults. The Journal of The American Medical Association . 2013
-
7C Sassy-Prigent,D Heudes,C M,et,MF Belair,O Michel,B Perdereau,J Bariety,P Brunev.Early glomerular macrophage recruitment in streptozotocin-induced diabetic rats. Diabetes . 2000
-
8Noronha I L,Fujihara C K,Zatz R.The inflammatory component in progressive renal disease-are interventions possible. Nephrology Dialysis Transplantation . 2002
-
9Leask A,Abraham DJ.TGF-beta signaling and the fibrotic response. The FASEB Journal . 2004
-
10Katherine R Tuttle.Linking metabolism and immunology:diabetic ne-phropathy is an inflammatory disease. Journal of the American Society of Nephrology . 2005
二级引证文献4
-
1曾嵘.血清IL-17与MMP-9在过敏性紫癜中的临床意义[J].河北医药,2015,37(8):1166-1168. 被引量:5
-
2罗劲松,刘宏,姜毅.孟鲁斯特对儿童过敏性紫癜患者血清中OPN和NF-κB表达水平的影响[J].实用临床医药杂志,2016,20(15):143-144. 被引量:6
-
3郭荣春,郭云静,贾晶晶.舒适护理对过敏性紫癜患儿心理及生理舒适度的影响分析[J].中西医结合护理(中英文),2016,2(6):69-71. 被引量:7
-
4张小华,朱小晖.小儿过敏性紫癜性肾炎临床特征及其相关危险因素分析[J].检验医学与临床,2017,14(16):2473-2475. 被引量:24
-
1宗可诚,张宏斌.通心络胶囊联合贝那普利治疗2型糖尿病肾病临床观察[J].医学新知,2010,20(5):481-482. 被引量:1
-
2牛荣华,刘冰,于奕蕾,郭瑞友.厄贝沙坦苯磺酸氨氯地平对糖尿病肾病合并高血压的疗效分析[J].中国医药科学,2013,3(19):78-80. 被引量:14
-
3向清,史伟,吴金玉,向彩春.贝那普利联合厄贝沙坦治疗糖尿病肾病疗效观察[J].中南药学,2008,6(4):490-493. 被引量:6
-
4张慧嫦,叶真.糖尿病肾病实验室检测指标进展[J].浙江中医药大学学报,2008,32(6):846-848. 被引量:4
-
5谢庆平.同型半胱氨酸、β2微球蛋白、α1微球蛋白及血清胱抑素联合检测对早期糖尿病肾病的诊断价值研究[J].特别健康(下),2014,0(10):144-145.
-
6刘忠伦,姜海涛,王小兰.糖尿病视网膜病变患者E-选择素检测的临床意义[J].现代检验医学杂志,2010,25(4):84-85. 被引量:4
-
7张志红,张坤丽.糖尿病性黄斑水肿与血清E-选择素的相关性分析[J].国际眼科杂志,2014,14(9):1697-1698. 被引量:4
-
8安学敏,罗卫强,夏颂年.血清可溶性E-选择素、超敏C-反应蛋白、血尿酸与急性心肌梗死的相关性研究[J].中国医疗前沿,2012,7(13):29-30. 被引量:1
-
9杨大春,曾智,张铭,刘瑞,李小丽,华军益.冠心病患者血清可溶性E-选择素检测的意义[J].中华老年心脑血管病杂志,2003,5(1):24-26.
-
10刘玉田,袁骞.糖尿肾病的早期检测[J].淮海医药,1998,16(2):39-39.