基于卒中登记的缺血性卒中亚型分布及危险因素分析

Analysis of risk factors and subtypes of ischemic stroke based on stroke registry

目的了解徐州地区缺血性卒中OCSP临床分型及M-TOAST病因分型及其相关危险因素,为该地区缺血性卒中的治疗及预防提供参考依据。方法运用卒中注册软件,采用前瞻性单中心登记方法,登记566例缺血性卒中患者的临床资料,研究缺血性卒中的亚型分布,并以卒中登记中96例出血性卒中患者为对照,研究缺血性卒中的相关危险因素。结果 566例缺血性卒中患者中,脑梗死505例,TIA61例。部分前循环是最多见的缺血性卒中亚型,共243例(48.12%)。脑梗死病因学分型M-TOAST分型中,动脉粥样硬化性血栓形成(AT)最多,共248例(49.11%)。高血压、吸烟、饮酒、高同型半胱氨酸是缺血性卒中最常见的危险因素。相对于出血性卒中,与缺血性卒中关系更为密切的是房颤、高同型半胱氨酸(OR=3.854,2.922)。结论本研究中缺血性卒中OCSP分型中部分前循环梗死最多见,其病因学分型动脉粥样硬化性血栓形成(AT)最多。相对出血性卒中,与缺血性卒中密切相关的是房颤、高同型半胱氨酸。

Objective To explore the difference in clinical manifestations,imaging characteristics between child and adult patients with moyamoya disease.Methods A retrospective study was performed in 30 children and 49 adults with moyamoya disease.Clinical manifestations and neuroimaging characteristics were comparatively analyzed.Results The ratio of the children with ischemic cerebrovascular disease as the first symptom was higher than that of the adults（P0.05）,while the ratio of the adults with hemorrhagic cerebrovascular disease as the first symptom was higher than that of the children（P0.05）.Conclusion There are differences of clinical symptoms,neuroimaging characteristics between child and adult patients with moyamoya disease,and it should be paid close attention to identification in clinical practice.