痰热清联合左氧氟沙星注射液治疗下呼吸感染67例疗效分析

THE EFFECT ANALYSIS OF THE COMBINATION TREATMENT OF TANREQING AND LEVOFLOXACIN INJECTION FOR LOWER RESPIRATORY TRACT INFECTION:A REPORT OF 67 CASES

目的观察痰热清注射液联合左氧氟沙星注射液治疗下呼吸道感染的临床疗效及安全性。方法将下呼吸道感染患者67例随机分为左氧氟沙星注射液治疗组(以下简称左氧氟沙星组)、左氧氟沙星注射液联合痰热清注射液治疗组(以下简称痰热清组)。所有患者治疗前、后进行症状评分,并对不良反应事件进行观察。结果痰热清组有效率为97.0%,显著高于左氧氟沙星组(79.4%),两组细菌清除率分别为94.4%和73.7%,无统计学差异(p>0.05)。两组不良事件发生率无统计学差异(p>0.05)。结论痰热清注射液联合左氧氟沙星注射液治疗下呼吸道感染临床效果显著,能够显著改善临床症状,安全有效。

Objective To investigate the clinical effect of TanReQing and Levofloxacin injection in treating lower respiratory tract infection. Methods 67 patients with lower respiratory tract infection were randomly divided in- to two groups. One is treated with Levofloxacin injection （hereafter called as Levofloxacin group）, another is treated with TanReQing and Levofloxacin injection （hereafter called as TanReQing group）. The symptoms scores were car- ried out before and after treatment for both groups, the adverse reaction is monitored as well. Results The efficacy of TanReQing group is 97.0%, which was significantly higher than Levofloxacin group （79.4%）. The germ clearance rate of both groups are 94.4% and 73.7% respectively, which has no significant difference （p 〉 0. 05）. The adverse reaction of two groups has no significant difference （p 〉 O. 05 ）. Conclusion The effect of TanReQing and Levoflox- acin injection in treating lower respiratory tract infection is obvious, which can effectively improve the patients＇ condition, so it is worthy of further clinical application.